Pharma-Bio

HIV Clinical Vaccine Facility | Project profile

About the client    

The client for this project is a non-profit organization providing innovative leadership and collaborative solutions for the global fight against infectious diseases

Scope of project    

Our team provided preliminary engineering services for the client’s 130,000 SF, $88 million, cGMP clinical production facility for HIV / AIDS vaccines, located in North America.


Services provided by Middough    

Middough's scope of services included process architecture layouts, process flow diagrams, equipment selection and a cost estimate. Process operations included microbial fermentation, cell culture with viral vectors and egg-based recombinant technologies, as well as separation and purification and aseptic filling.


Results delivered to client    

This integrated facility is designed to support and accelerate process development and clinical trials for many highly promising candidate vaccines, following laboratory-based discovery and screening.

Process operations included microbial fermentation, cell culture with viral vectors and egg-based recombinant technologies, as well as separation and purification and aseptic filling

The facility was designed to BSL-3/2 criteria.